Salinomycin
Product Specifications
CAS Number
53003-10-4
Target
Autophagy|||Mitophagy|||Parasite|||Apoptosis|||Antibacterial|||Wnt/beta-catenin|||Antibiotic
Related Pathways
Microbiology/Virology|||Cytoskeletal Signaling|||Stem Cells|||Apoptosis|||Autophagy
Purity
0.98
Bioactivity
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria, acts as a potent inhibitor of Wnt/?-catenin signaling by blocking Wnt-induced LRP6 phosphorylation, and demonstrates selective activity against human cancer stem cells.
Smiles
[H][C@@]1(CC[C@H](C)[C@@]([H])(O1)[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@]1([H])O[C@@]2(O[C@@]3(CC[C@](C)(O3)[C@@]3([H])CC[C@](O)(CC)[C@H](C)O3)[C@H](O)C=C2)[C@H](C)C[C@@H]1C)[C@@H](CC)C(O)=O
Molecular Formula
C42H70O11
Molecular Weight
751
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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