Lenvatinib
Product Specifications
CAS Number
417716-92-8
Target
C-RET, VEGFR, FGFR, PDGFR, c-Kit
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis
Purity
0.9996
Bioactivity
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM) . Lenvatinib has strong anti-tumor activity.
Smiles
O(C=1C2=C(C=C(OC)C(C(N)=O)=C2)N=CC1)C3=CC(Cl)=C(NC(NC4CC4)=O)C=C3
Molecular Formula
C21H19ClN4O4
Molecular Weight
426.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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