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Abexinostat

Product Specifications

CAS Number

783355-60-2

Target

HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Purity

0.9843

Bioactivity

PCI-24781 (Abexinostat (PCI24781) ) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.

Smiles

CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO

Molecular Formula

C21H23N3O5

Molecular Weight

397.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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