Abexinostat
Product Specifications
CAS Number
783355-60-2
Target
HDAC
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9843
Bioactivity
PCI-24781 (Abexinostat (PCI24781) ) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
Smiles
CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
Molecular Formula
C21H23N3O5
Molecular Weight
397.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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