Bosutinib
Product Specifications
CAS Number
380843-75-4
Target
Autophagy, Bcr-Abl, Src
Related Pathways
Autophagy, Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Purity
0.9993
Bioactivity
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.
Smiles
N(C=1C2=C(C=C(OCCCN3CCN(C)CC3)C(OC)=C2)N=CC1C#N)C4=CC(OC)=C(Cl)C=C4Cl
Molecular Formula
C26H29Cl2N5O3
Molecular Weight
530.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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