UK-124114
Product Specifications
CAS Number
165108-07-6
Target
GABA Receptor, Others
Related Pathways
Neuroscience, Others, Membrane transporter/Ion channel
Purity
0.9944
Bioactivity
UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, selamectin (0.1 μg/ml) shows the effect of growth inhibition.
Smiles
O[C@@]1\2[C@]3(C(=NO)C(C)=C[C@]1(C(=O)O[C@@]4(C[C@@]5(O[C@@H]([C@@H](C)CC5)[C@H]6CCCCC6)O[C@@](C4)(C/C=C(\C)/[C@@H](O[C@H]7C[C@H](OC)[C@@H](O)[C@H](C)O7)[C@@H](C)/C=C\C=C2\CO3)[H])[H])[H])[H]
Molecular Formula
C43H63NO11
Molecular Weight
769.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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