Desoxycarbadox

Desoxycarbadox is a metabolite of Carbadox (HY-B1340) . Carbadox is a quinoxaline-di-N-oxide antibiotic compound[1][2].

Product Specifications

CAS Number

[55456-55-8]

UNSPSC

12352005

Hazard Statement

H228, H302, H350

Target

Antibiotic; Drug Metabolite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/desoxycarbadox.html

Purity

95.54

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=NC2=CC=CC=C2N=C1)OC

Molecular Formula

C11H10N4O2

Molecular Weight

230.22

Precautions

H228, H302, H350

References & Citations

[1]MacIntosh AI, et al. Liquid chromatographic monitoring of the depletion of carbadox and its metabolite desoxycarbadox in swine tissues. J Assoc Off Anal Chem. 1985;68 (4) :665-671.|[2]Looft T, et al. Carbadox has both temporary and lasting effects on the swine gut microbiota. Front Microbiol. 2014;5:276. Published 2014 Jun 10.|[3]Zhang K, et al. Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites. Environ Toxicol Pharmacol. 2015;39 (2) :555-567.