TLR8 rabbit pAb
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q9NR97
Swiss Prot
Q9NR97
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of TLR8
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Dilution
IHC: 1:200-500
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endosome membrane ; Single-pass type I membrane protein . Endosomal localization confers distinctive proteolytic processing. .
Other Product Names
Toll-like receptor 8; CD288
Gene ID (Human)
51311
Available Sizes
Frequently Asked Questions
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