Pramocaine (hydrochloride)
Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses.
Product Specifications
CAS Number
637-58-1
Product Name Alternative
Pramoxine hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Pramocaine-hydrochloride.html
Concentration
10mM
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CCCCOC1=CC=C(OCCCN2CCOCC2)C=C1.[H]Cl
Molecular Formula
C17H28ClNO3
Molecular Weight
329.86
Precautions
H302, H315, H319, H335
References & Citations
[1]SCHMIDT JL, et al. The pharmacology of pramoxine hydrochloride: a new topical local anesthetic. Curr Res Anesth Analg. 1953 Nov-Dec;32 (6:1) :418-25.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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