Pramocaine (hydrochloride)

Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses.

Product Specifications

CAS Number

[637-58-1]

Product Name Alternative

Pramoxine hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pramocaine-hydrochloride.html

Concentration

10mM

Purity

99.74

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CCCCOC1=CC=C(OCCCN2CCOCC2)C=C1.[H]Cl

Molecular Formula

C17H28ClNO3

Molecular Weight

329.86

Precautions

H302, H315, H319, H335

References & Citations

[1]SCHMIDT JL, et al. The pharmacology of pramoxine hydrochloride: a new topical local anesthetic. Curr Res Anesth Analg. 1953 Nov-Dec;32 (6:1) :418-25.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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