Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Vinorelbine (ditartrate)

Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

Product Specifications

CAS Number

125317-39-7

Product Name Alternative

KW-2307; Nor-5'-anhydrovinblastine ditartrate

UNSPSC

12352005

Hazard Statement

H317

Target

Autophagy; Microtubule/Tubulin

Type

Natural Products

Related Pathways

Autophagy; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Vinorelbine-ditartrate.html

Purity

99.94

Solubility

DMSO : 175 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C4=C5C(C=CC=C6)=C6N4)(CC(C=C(CC)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Molecular Formula

C53H66N4O20

Molecular Weight

1079.11

Precautions

H317

References & Citations

[1]Ngan VK, et al. Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine. Mol Pharmacol. 2001 Jul;60 (1) :225-32.|[2]Liu XM, et al. Unique induction of p21 (WAF1/CIP1) expression by vinorelbine in androgen-independent prostate cancer cells. Br J Cancer. 2003 Oct 20;89 (8) :1566-73.|[3]Poirier VJ, et al. Toxicity, dosage, and efficacy of vinorelbine (Navelbine) in dogs with spontaneous neoplasia. J Vet Intern Med. 2004 Jul-Aug;18 (4) :536-9.|[4]Pierro JA, et al. Phase I clinical trial of vinorelbine in tumor-bearing cats. J Vet Intern Med. 2013 Jul-Aug;27 (4) :943-8.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

Launched

Citation 01

Acta Pharmacol Sin. 2024 Oct;45 (10) :2174-2185.|Adv Ther. 2024 Jul 18.|Biochem Biophys Res Commun. 2020 May 21;526 (1) :154-157.|bioRxiv. 2025 Aug 27.|Cell Mol Immunol. 2023 Jan;20 (1) :51-64.|Cell Rep Med. 2025 Apr 2:102053.|EBioMedicine. 2021 Aug:70:103510.|Int J Cancer. 2024 Jul 15;155 (2) :324-338.|iScience. 2022 Sep 6;25 (10) :105081.|Microb Cell Fact. 2025 Jan 30;24 (1) :34.|Res Sq. 2025 May 16:rs.3.rs-6590535.|Sci Adv. 2023 Jun 2;9 (22) :eadc9273.|Transl Lung Cancer Res. 2024 Oct 31;13 (10) :2698-2712.|Am J Cancer Res. 2021 Apr 15;11 (4) :1428-1445.|Biochem Pharmacol. 2020 May;175:113865.|Cancers (Basel) . 2021 Jul 2;13 (13) :3323.|J Bone Oncol. 2021 Sep 20:30:100391.|Microsyst Nanoeng. 2021 May 24:7:38.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF488A conjugate, 0.1mg/mL
BNC880965-100 1x 100 µL

MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF405S conjugate, 0.1mg/mL
BNC040806-500 1x 500 µL

TYRP1 (Tyrosinase Related Protein 1) (TA99), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
MART-1 / Melan-A (M2-7C10), CF740 conjugate, 0.1mg/mL
BNC740009-500 1x 500 µL

MART-1 / Melan-A (M2-7C10), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Fibronectin (TV-1), CF647 conjugate, 0.1mg/mL
BNC470029-500 1x 500 µL

Fibronectin (TV-1), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Major Vault Protein (MVP) (1032), 1mg/mL
BNUM0225-50 1x 50 µL

Major Vault Protein (MVP) (1032), 1mg/mL

Sign In for Pricing
View Details
Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) (KRT20/1993), CF647 conjugate, 0.1mg/mL
BNC471993-100 1x 100 µL

Cytokeratin 20 (KRT20) (Colorectal Epithelial Marker) (KRT20/1993), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details