Hydroxy-Dynasore
Hydroxy Dynasore (Dyngo-4a), a structural mimetic analog of Dynasore , is an improved, less cytotoxic and versatile dynamin inhibitor with IC50 values of 0.38 μM and 2.3 μM for brain recombinant dynamin I and recombinant mouse dynamin II, respectively. Hydroxy Dynasore inhibits dynamin-dependent transferrin endocytosis with an IC50 of 5.7 μM.
Product Specifications
CAS Number
1256493-34-1
Product Name Alternative
Dyngo-4a
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Dynamin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hydroxy-dynasore.html
Purity
99.11
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC2=CC=CC=C2C=C1C(N/N=C/C3=C(O)C=C(O)C(O)=C3)=O
Molecular Formula
C18H14N2O5
Molecular Weight
338.31
Precautions
H302, H312, H332
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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