Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Citalopram-d3 (hydrobromide)

Citalopram-d3 ((±) -Citalopram-d3) hydrobromide is deuterium labeled Citalopram (hydrobromide) . Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI) . Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM. Antidepressant effect[1][2].

Product Specifications

Product Name Alternative

(±) -Citalopram hydrobromide-d3; Lu 10-171-d3

UNSPSC

12352005

Target

Autophagy; Isotope-Labeled Compounds; Serotonin Transporter

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Smiles

N#CC1=CC2=C(C(CCCN(C)C([2H])([2H])[2H])(C3=CC=C(F)C=C3)OC2)C=C1.Br

Molecular Formula

C20H19D3BrFN2O

Molecular Weight

408.32

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]J Hyttel. Citalopram--pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6 (3) :277-95.|[3]Laurent Sakka, et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8 (26) :42789-42807.|[4]F Pollier, et al. Serotonin reuptake inhibition by citalopram in rat strains differing for their emotionality. Neuropsychopharmacology. 2000 Jan;22 (1) :64-76.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)
MBS7010490-01 0.02 mg

Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)

Sign In for Pricing
View Details
Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)
MBS7010490-02 0.1 mg

Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)

Sign In for Pricing
View Details
Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)
MBS7010490-03 5x 0.1 mg

Recombinant Saccharomyces cerevisiae Bud site selection protein 9 (BUD9)

Sign In for Pricing
View Details
RPS27AP7 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
LV784641 1.0 µg DNA

RPS27AP7 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

Sign In for Pricing
View Details
TRAK1 (NM_001042646) Human Tagged ORF Clone Lentiviral Particle
RC224330L4V 200 µL

TRAK1 (NM_001042646) Human Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
RASGRF1 Rabbit pAb
E2506964 100 µL

RASGRF1 Rabbit pAb

Sign In for Pricing
View Details