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Cytidine 5'-diphosphate (trisodium salt)

Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK) . Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

Product Specifications

CAS Number

[34393-59-4]

Product Name Alternative

CDP

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cytidine-5-diphosphate-trisodium-salt.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 250 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H](O1)COP(OP(O[Na])(O[Na])=O)(O[Na])=O)[C@@H](O)[C@@H]1N2C=CC(N)=NC2=O

Molecular Formula

C9H12N3Na3O11P2

Molecular Weight

469.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018.|[2]Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417 (4) :431-47.|[3]Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65 (10) :1295-1306.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

Phase 2

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