Lascufloxacin

Lascufloxacin (KRP-AM1977X) is a potent and orally active fluoroquinolone antibacterial agent. Lascufloxacin potently inhibits infections caused by various pathogens, including quinolone-resistant strains. Lascufloxacin has the potential for various infectious diseases treatment, including lower respiratory tract infections[1][2].

Product Specifications

CAS Number

[848416-07-9]

Product Name Alternative

KRP-AM1977

UNSPSC

12352005

Target

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lascufloxacin.html

Purity

98.04

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CN(CCF)C2=C(C=C(F)C(N3C[C@H](CNC4CC4)[C@H](F)C3)=C2OC)C1=O)O

Molecular Formula

C21H24F3N3O4

Molecular Weight

439.43

References & Citations

[1]Kishii R, et al. In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977) . Antimicrob Agents Chemother. 2017 May 24;61 (6) . pii: e00120-17.|[2]Furuie H, et al. Intrapulmonary Pharmacokinetics of Lascufloxacin in Healthy Adult Volunteers. Antimicrob Agents Chemother. 2018 Mar 27;62 (4) . pii: e02169-17.