DYR684f
Product Specifications
CAS Number
3038488-10-4
UNSPSC Description
DYR684f is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates) of DYR684 (HY-168194)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dyr684e-co-piperidine-py-ethyne-c-br.html
Smiles
O=C(C(N(C(C1=C2C=CC=C1NCC3=CN(C4CCN(C(C5CCN(C6=NC=C(I)C=C6)CC5)=O)CC4)N=C3)=O)C2=O)CC7)NC7=O
Molecular Weight
750.59
References & Citations
[1]Gerrit Wilms, et al. Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B. J Med Chem. 2024 Oct 10;67(19):17259-17289.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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