Vanillyl alcohol

Vanillyl alcohol (p- (Hydroxymethyl) guaiacol) is an orally active phenolic alcohol. Vanillyl alcohol reduces ROS generation. suppresses Bax, increases Bcl-2. Vanillyl alcohol has anti-angiogenic, anti-inflammatory, anti-nociceptive and neuroprotective effects. Vanillyl alcohol is used as a flavoring agent in foods and beverages[1][2][3].

Product Specifications

CAS Number

[498-00-0]

Product Name Alternative

P- (Hydroxymethyl) guaiacol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bcl-2 Family; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/vanillyl-alcohol.html

Purity

99.72

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCC1=CC=C(O)C(OC)=C1

Molecular Formula

C8H10O3

Molecular Weight

154.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Chen Z, et al. Establishing an Artificial Pathway for De Novo Biosynthesis of Vanillyl Alcohol in Escherichia coli. ACS Synth Biol. 2017 Sep 15;6 (9) :1784-1792.|[2]Jung HJ, et al. Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol. Arch Pharm Res. 2008 Oct;31 (10) :1275-9. |[3]Kim IS, et al. Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells. Molecules. 2011 Jun 24;16 (7) :5349-61.