Mal-PEG4-VCP-NB

Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB[1].

Product Specifications

CAS Number

[1345681-54-0]

UNSPSC

12352203

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-peg4-vcp-nb.html

Smiles

O=C(C=CC1=O)N1CCOCCOCCOCCOC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O)=O

Molecular Formula

C38H49N7O15

Molecular Weight

843.83

References & Citations

[1]Beusker P H, et al. Novel conjugates of CC-1065 analogs and bifunctional linkers[P]. 2011-10-27.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Protease Cleavable Linker

Curated Selection

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