Mal-PEG4-VCP-NB
Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB[1].
Product Specifications
CAS Number
[1345681-54-0]
UNSPSC
12352203
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg4-vcp-nb.html
Smiles
O=C(C=CC1=O)N1CCOCCOCCOCCOC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O)=O
Molecular Formula
C38H49N7O15
Molecular Weight
843.83
References & Citations
[1]Beusker P H, et al. Novel conjugates of CC-1065 analogs and bifunctional linkers[P]. 2011-10-27.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Curated Selection
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