Acridone-4-carboxylic acid
Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].
Product Specifications
CAS Number
[24782-64-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/acridone-4-carboxylic-acid.html
Purity
98.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(C=CC=C1C2=O)=C1NC3=C2C=CC=C3)O
Molecular Formula
C14H9NO3
Molecular Weight
239.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21 (12) :3563-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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