hMAO-B-IN-4
Product Specifications
UNSPSC Description
hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].
Target Antigen
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-in-4.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CS1)/C=C/C2=CC=C(C=C2)OCC3=CC=CC=C3
Molecular Weight
320.40
References & Citations
[1]Sudevan ST, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152671/hMAO-B-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152671/hMAO-B-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1666119-75-0
Available Sizes
Curated Selection
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