Asimilobine
Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity[1][2].
Product Specifications
CAS Number
6871-21-2
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor; Parasite
Type
Natural Products
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/asimilobine.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
OC1=C(OC)C2=C3C(CCN[C@]3([H])CC4=CC=CC=C24)=C1
Molecular Formula
C17H17NO2
Molecular Weight
267.32
References & Citations
[1]N Shoji, et al. Asimilobine and Lirinidine, Serotonergic Receptor Antagonists, From Nelumbo Nucifera. J Nat Prod. Jul-Aug 1987;50 (4) :773-4.|[2]Chun-Mei Jin, et al. Effects of Asimilobine on Dopamine Biosynthesis and l-DOPA-induced Cytotoxicity in PC12 Cells. J Asian Nat Prod Res. Jul-Aug 2008;10 (7-8) :747-55.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Dopamine Receptor; MUC4; Plasmodium
Available Sizes
Frequently Asked Questions
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