2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[908129-24-8]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluoro-β-d-arabino-6-azauridine.html
Purity
96.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](F)[C@H](N2C(NC(C=N2)=O)=O)O[C@@H]1CO
Molecular Formula
C8H10FN3O5
Molecular Weight
247.18
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
SOX5 CRISPR Knock Out 293T Cell Line (Human)
Ncbp1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)