2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine
2’-Deoxy-2’-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[908129-24-8]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-deoxy-2-fluoro-β-d-arabino-6-azauridine.html
Purity
96.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](F)[C@H](N2C(NC(C=N2)=O)=O)O[C@@H]1CO
Molecular Formula
C8H10FN3O5
Molecular Weight
247.18
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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