2-Iminothiolane (hydrochloride)

2-Iminothiolane hydrochloride is a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycan. 2-Iminothiolane hydrochloride can be used to modify proteins and peptides[1][2].

Product Specifications

CAS Number

[4781-83-3]

UNSPSC

12352200

Hazard Statement

H301

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-iminothiolane-hydrochloride.html

Purity

99.92

Solubility

DMSO : 14.29 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

N=C1CCCS1.Cl

Molecular Formula

C4H8ClNS

Molecular Weight

137.63

Precautions

H301

References & Citations

[1]A L Tarentino, et al. 2-Iminothiolane: a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans. Glycobiology. 1993 Jun;3 (3) :279-85.|[2]Singh R, et al. Formation of N-substituted 2-iminothiolanes when amino groups in proteins and peptides are modified by 2-iminothiolane. Anal Biochem. 1996 Apr 5;236 (1) :114-25.