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Integrin alpha V + beta 6 Antibody

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Product Specifications

UniProt

P06756, P18564

Reactivity

Human

Immunogen

Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.

Clonality

Monoclonal

Clone

AvB6 53a.2

Conjugation

Unconjugated

Purification

Protein G affinity chromatography

Dilution

Immunoprecipitation: 1-2ug/500ug protein, Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2ug/ml, Western blot: 0.5-1ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher.

Tested Applications

FACS, IF, IP, WB

Host or Source

Rat

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Rat IgG2a, kappa

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