HHV8 Antibody / Herpes Virus 8
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
Product Specifications
Reactivity
Virus
Immunogen
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.
Clonality
Monoclonal
Clone
LN53
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology
Purification
Protein G affinity chromatography
Dilution
Immunofluorescence: 1-3ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the human HHV8 antibody should be determined by the researcher.
Tested Applications
ELISA, IF, IHC-P
Host or Source
Rat
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rat IgG2c, kappa
Frequently Asked Questions
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