Melanoma Marker Antibody Cocktail (MART-1 & Tyrosinase & gp100)
Selected Variant
GTR18575123
Size: 100 µg
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
Reactivity
Human
Immunogen
Clonality
Monoclonal
Clone
DT101+ BC199 + T311 + HMB45
Conjugation
Unconjugated
Field of Research
Cancer Biology; Cell Biology
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Melanoma Marker antibody cocktail should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
IgG1, IgG2a, IgG2b / kappa, lambda
Price
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