CD3e Antibody
CD3 chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vivo T cell depletion.
Product Specifications
UniProt
P07766
Reactivity
Mouse
Immunogen
The H2Kb-specific mouse cytotoxic T lymphocyte clone BM10 37 was used as the immunogen for the CD3e antibody.
Clonality
Monoclonal
Clone
145-2C11
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A affinity chromatography
Dilution
Functional Studies (order BSA/azide-free format), Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD3e antibody should be determined by the researcher.
Tested Applications
FACS, Functional Studies, IF
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Armenian Hamster IgG, kappa
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytokeratin 19 (ready to use) Mouse Monoclonal Antibody
Cytokeratin 19 (ready to use) Mouse Monoclonal Antibody
