Uzarigenin
Product Specifications
UNSPSC Description
Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC50 values of 0.3 μM, 3.0 μM, 8.0 μM, 6.0 μM and 6.0 μM respectively[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uzarigenin.html
Solubility
10 mM in DMSO
Smiles
O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@@]5([H])C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]23C)=C1
Molecular Weight
374.51
References & Citations
[1]Hosseini SH, et al. Antiproliferative Cardenolides from the Aerial Parts of Pergularia tomentosa. J Nat Prod. 2019 Jan 25;82(1):74-79.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1107/Uzarigenin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1107/
Clinical Information
No Development Reported
CAS Number
466-09-1
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