Bax Antibody
Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Product Specifications
UniProt
Q07812
Reactivity
Human
Immunogen
Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody.
Clonality
Monoclonal
Clone
SPM336
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Western blot: 1-2ug/ml, Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Tested Applications
FACS, IF, IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![N-{[5- (Pyrrolidin-2-yl) furan-2-yl]methyl}acetamide](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
N-{[5- (Pyrrolidin-2-yl) furan-2-yl]methyl}acetamide
N-{[5- (Pyrrolidin-2-yl) furan-2-yl]methyl}acetamide
Recombinant Vibrio Cholerae psd Protein (aa 1-251) (strain M66-2)