What is the catalog number for Ornithine Decarboxylase Antibody?

The catalog number for Ornithine Decarboxylase Antibody is orb2645089.

What sizes are available for Ornithine Decarboxylase Antibody?

Ornithine Decarboxylase Antibody is available in the following size(s): 100 µg.

Is Ornithine Decarboxylase Antibody in stock?

Ornithine Decarboxylase Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Ornithine Decarboxylase Antibody

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Product Specifications

UniProt

P11926

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for this ODC-1 antibody.

Clonality

Monoclonal

Clone

SPM565

Conjugation

Unconjugated

Field of Research

Pharmacology & Drug Discovery

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The optimal dilution of the Ornithine Decarboxylase antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.