Isocorydine (hydrochloride)

Isocorydine hydrochloride is isolated from Dicranostigma leptopodum (Maxim.) Fedde (DLF) . Isocorydine hydrochloride combines with Doxorubicin (DOX) has a promising potential to eradicate hepatocellular carcinoma (HCC) [1].

Product Specifications

CAS Number

[13552-72-2]

UNSPSC

12352005

Hazard Statement

H302

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isocorydine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

COC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24.[H]Cl

Molecular Formula

C20H24ClNO4

Molecular Weight

377.86

Precautions

P264-P270-P330-P501

References & Citations

[1]Pan JX, et al. Isocorydine suppresses doxorubicin-induced epithelial-mesenchymal transition via inhibition of ERK signaling pathways in hepatocellular carcinoma. Am J Cancer Res. 2018 Jan 1;8 (1) :154-164. eCollection 2018.