Recombinant Insulin-like Growth Factor 1 Antibody / IGF-1
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Product Specifications
UniProt
P05019
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full-length human protein was used as the immunogen for the recombinant Insulin-like Growth Factor 1 antibody.
Clonality
Recombinant
Clone
IGF1/2872R
Conjugation
Unconjugated
Field of Research
Metabolism Research; Stem Cell & Developmental Biology
Purification
Protein A affinity chromatography
Dilution
Flow cytometry: 1-2ug/10^6 cells in 0.1ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant Insulin-like Growth Factor 1 antibody should be determined by the researcher.
Tested Applications
FACS
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG
Frequently Asked Questions
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