[Asp371]-Tyrosinase (369-377), human
Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].
Product Specifications
CAS Number
168650-46-2
UNSPSC
12352209
Target
Tyrosinase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/asp371-tyrosinase-369-377-human.html
Purity
99.66
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)[C@@H](C)O)=O)=O)CC(O)=O)=O)CCSC)=O)N)C=C1
Molecular Formula
C42H66N10O16S2
Molecular Weight
1031.16
References & Citations
[1]Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189 (7) :3538-47.|[2]Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20 (4) :1075-86.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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