Ornithine Decarboxylase, Human Recombinant

ODC is pyridoxal phosphate dependent amino acid deacarboxylase, which catalyzes the conversion of ornithine to putrescine. It is the first and rate-limiting step in the polyamine biosynthetic pathway. Polyamines are involved in processes such as cell growth, differentiation and synthesis of macromolecules. Overexpression of ODC is known to play role in cancers and inflammation.