Homocysteine α,γ-Lyase (rHCYase), Active, Recombinant

Recombinant Homocysteine α,γ-lyase is a pyridoxal-5’-phosphate dependent enzyme. It is a mutant of homocysteinase from Trichomonas vaginalis encoded by mgl1 gene, containing three point mutations, such as; Phe47Leu, Asp172Glu, Ser308Tyr. Its native molecular mass is 170 kD, with four seemingly identical subunits, each with molecular mass of 43-45 kD. The enzyme can metabolize homocysteine into α-keto butyrate, hydrogen sulfide and ammonia.