Elvitegravir
Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
Product Specifications
CAS Number
697761-98-1
Product Name Alternative
GS-9137; JTK-303; D06677
UNSPSC
12352005
Hazard Statement
H315, H319
Target
HIV; HIV Integrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Elvitegravir.html
Purity
99.90
Solubility
DMSO : 233.33 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CN(C2=C(C1=O)C=C(C(OC)=C2)CC3=CC=CC(Cl)=C3F)[C@@H](C(C)C)CO
Molecular Formula
C23H23ClFNO5
Molecular Weight
447.88
Precautions
H315, H319
References & Citations
[1]Shimura K, et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137) . J Virol. 2008 Jan;82 (2) :764-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HIV-1; HIV-2
Available Sizes
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