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Pitofenone hydrochloride

Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively[1][2].

Product Specifications

CAS Number

[1248-42-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H360

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pitofenone_hydrochloride.html

Purity

99.88

Solubility

DMSO : 83.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

Cl[H].O=C(C1=CC=C(C=C1)OCCN2CCCCC2)C3=C(C=CC=C3)C(OC)=O

Molecular Formula

C22H26ClNO4

Molecular Weight

403.90

Precautions

H302, H315, H319, H335, H360

References & Citations

[1]Punekar NS, et al. Acetylcholinesterase inhibition by pitofenone: a spasmolytic compound. Biotechnol Appl Biochem. 1991 Dec;14 (3) :378-82.|[2]https://journals.lww.com/iphr/abstract/1998/30050/antispasmodic_activity_of_diclofenac_and_its.6.aspx

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE

Available Sizes

Curated Selection

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