(S) -mchm5U
(S) -mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S) -mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S) -mchm5U can be used for RNA modification synthesis[1].
Product Specifications
CAS Number
[89665-83-8]
UNSPSC
12352005
Target
Drug Isomer
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-mchm5u.html
Purity
98.87
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
O=C(N(C=C1[C@@H](C(OC)=O)O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)NC1=O
Molecular Formula
C12H16N2O9
Molecular Weight
332.26
References & Citations
[1]van den Born E, et al. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. Nat Commun. 2011 Feb 1;2:172.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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