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MCU-i11

Product Specifications

UNSPSC Description

MCU-i11 is a negative regulator of the mitochondrial calcium uniporter (MCU) complex. MCU-i11 can reduce mitochondrial Ca2+ uptake. MCU-i11 impairs muscle cell growth[1].

Target Antigen

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mcu-i11.html

Purity

98.42

Solubility

DMSO : 87.5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(NC1=CC=C(OCC)C=C1)CN2C(N(CC3=CC=CC=C3)C(C4=C2SC5=C4CCN(C(C)=O)C5)=O)=O

Molecular Weight

532.61

References & Citations

[1]Di Marco G, et al. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Cell Rep. 2020 Feb 18;30(7):2321-2331.e6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W194810/MCU-i11-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W194810/MCU-i11-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

902903-59-7

Available Sizes

Curated Selection

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