Bleomycin A5

Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite[1][2].

Product Specifications

CAS Number

[11116-32-8]

Product Name Alternative

Pingyangmycin

UNSPSC

12352005

Target

Antibiotic; Apoptosis

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bleomycin-a5.html

Purity

99.81

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC1=NC(C2=NC(C(NCCCNCCCCN)=O)=CS2)=CS1)=O)=O)[C@@H](NC(C3=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C3C)=O)[C@H](C4=CN=CN4)O[C@H](O[C@H]5CO)[C@H]([C@H]([C@@H]5O)O)O[C@H](O[C@@H]6CO)[C@H]([C@H]([C@@H]6O)OC(N)=O)O

Molecular Formula

C57H89N19O21S2

Molecular Weight

1440.56

References & Citations

[1]Yaowu Yang, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53 (1) :150-5. |[2]Lin Fu-Tian, et al. Antitumor activity and preclinical pharmacological study of pingyangmycin. Zhonghua Zhongliu Zazhi. Volume: 1. Issue: 3. Pages: 161-6. Journal; English Abstract; Article. 1979.