MIA-2, human recombinant

MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF- and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.