FTY720 (S) -Phosphate
FTY720 (S) -Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.
Product Specifications
CAS Number
402616-26-6
Product Name Alternative
(S) -FTY720P; (S) -FTY720 phosphate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H336
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/FTY720__S_-Phosphate.html
Purity
99.57
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : < 0.1 mg/mL
Smiles
OC[C@](CCC1=CC=C(CCCCCCCC)C=C1)(N)COP(O)(O)=O
Molecular Formula
C19H34NO5P
Molecular Weight
387.45
Precautions
H302, H315, H319, H335, H336
References & Citations
[1]Wang L, et al. FTY720 (s) -phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. Crit Care Med. 2014 Mar;42 (3) :e189-99.|[2]Lingling Jia, et al. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 2017 Oct 19;8:1345.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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