Unifiram
Unifiram (DM232) is acts as a potent cognition enhancer through the activation of the AMPA-mediated neurotransmission system. Unifiram (DM232) has the potential for amnesia prevention and neurodegenerative disorder research[1][2].
Product Specifications
CAS Number
272786-64-8
Product Name Alternative
DM232
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/unifiram.html
Purity
99.78
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1CCC2CN(S(=O)(C3=CC=C(F)C=C3)=O)CCN21
Molecular Formula
C13H15FN2O3S
Molecular Weight
298.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Elisabetta Martini, et al. Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. Bioorg Med Chem. 2008 Dec 1;16 (23) :10034-42. |[2]N Galeotti, et al. AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram) . Naunyn Schmiedebergs Arch Pharmacol
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor
Available Sizes
Frequently Asked Questions
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