Unifiram

Unifiram (DM232) is acts as a potent cognition enhancer through the activation of the AMPA-mediated neurotransmission system. Unifiram (DM232) has the potential for amnesia prevention and neurodegenerative disorder research[1][2].

Product Specifications

CAS Number

[272786-64-8]

Product Name Alternative

DM232

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/unifiram.html

Purity

99.78

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1CCC2CN(S(=O)(C3=CC=C(F)C=C3)=O)CCN21

Molecular Formula

C13H15FN2O3S

Molecular Weight

298.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Elisabetta Martini, et al. Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators. Bioorg Med Chem. 2008 Dec 1;16 (23) :10034-42. |[2]N Galeotti, et al. AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram) . Naunyn Schmiedebergs Arch Pharmacol