RELM-beta, human recombinant

Human RELM β (Resistin-like molecule β/FIZZ2) is a new member to the family of adipocyte secreted proteins called adipocytokines. This family includes the RELM α, RELM β and Resistin molecules. Interestingly, RELM β and Resistin share similar characteristics such as an additional cysteine residue within the variable N-terminal region and are both homodimeric proteins. However, the RELM β is expressed only in the gastrointestinal track; especially the colon, while the Resistin and RELM β are secreted exclusively by adipocytes. Currently, the biological function of these proteins, as well as their molecular targets is largely unknown. Recombinant Human RELM β is a disulfide-linked homodimer with a total molecular weight of 11.0 kDa, consisting of 90 amino acid residue chains.