Thiabendazole-13C6
Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
Product Specifications
CAS Number
2140327-29-1
Product Name Alternative
2- (4-Thiazolyl) benzimidazole-13C6
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Mitochondrial Metabolism; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/thiabendazole-13c6.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CSC=N2)=N[13C]3=[13CH][13CH]=[13CH][13CH]=[13C]3N1
Molecular Formula
C4 13C6H7N3S
Molecular Weight
207.20
References & Citations
[1]Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10 (8) : p. e1001379.|[2]Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68 (12) : p. 962-8.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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