Adipophilin, human, recombinant

Adipophilin is a 49 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47, S3-12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. ADFP is expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. ADFP expression has a role in clear cell renal carcinoma differentiation. Most recently, it has been discovered that patients with kidney cancers had high levels of ADFP in their urine, suggesting that ADFP could be an excellent marker for kidney cancer.