IL-19, human recombinant

Interleukin-19 (IL-19) is a member of the IL-10 family produced by resting B cells and monocytes. IL-19 is thought to be up-regulated when monocytes are treated with GM-CSF or LPS. IL-19 shares a receptor complex with IL-20, and acts to induce IL-6 and TNF-α production by monocytes and promotes the Th2 response. Recombinant human IL-19 is a nonglycosylated protein, containing 155 amino acids, with a molecular weight of 17.9 kDa.