Valifenalate

Valifenalate (IR5885; Valiphenal) is an insecticide agent and fungicide, which is approved for application on high-value crops such as grapes, tomatoes and other vegetables. Valifenalate interferes with cell-wall synthesisValifenalate is effective against various types of mildew. Valifenalate can be used against crown rot of rose cuased by Phytophthora citrophthora. Valifenalate induces non-adverse thyroid changes via adaptive induction of uridine 5’-diphosphoglucuronosyltransferase (UGT) in the liver of dogs and rats[1][2][3].

Product Specifications

CAS Number

[283159-90-0]

Product Name Alternative

IR5885; Valiphenal

UNSPSC

12352005

Hazard Statement

H351, H411

Target

Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Valifenalate.html

Concentration

10mM

Purity

98.09

Solubility

DMSO : ≥ 41 mg/mL

Smiles

O=C([C@H](C(C)C)NC(OC(C)C)=O)NC(C1=CC=C(Cl)C=C1)CC(OC)=O

Molecular Formula

C19H27ClN2O5

Molecular Weight

398.88

Precautions

H351, H411

References & Citations

[1]HOFFMAN, Thomas, James., et al. FUNGICIDAL COMPOSITIONS. WO 2018 219773 A1|[2]A. Salamone, et al., Efficacy of the fungicide valifenalate against crown rot of rose caused by Phytophthora citrophthora. Modern fungicides and antifungal compounds VII. Proceedings of the 17th International Reinhardsbrunn Symposium, April 21-25 2013, 2014.|[3]Christine Walter, et al., Valifenalate-induced non-adverse thyroid changes via adaptive induction of uridine 5′-diphospho-glucuronosyltransferase (UGT) in the liver of dogs and rats but not humans. Toxicology and Applied Pharmacology, 2025.